BioPen Allows Surgeons To Draw And Repair Bones Inside Patient’s Body

We have been talking about 3D printing a lot lately and well, why shouldn’t we? It is proving to be the next big thing. As we’ve repeatedly mentioned; medical is the field thats gaining the most from the advancements in technology. We are witnessing new and improved treatment methods, cures for diseases and implementation of technology like never before. Our today’s post is about a new gadget that employs 3D printing and will be a must for any surgeon soon enough.

This particular gadget is being called a “BioPen” and it will enable doctors to actually ‘draw’ growth factors and live cells right onto the injury area. This gadget has been developed at the University of Wollongong (UOW) in Australia and its target market are the surgeons.

By Perseverance Tavagwisa

The idea is to speed up the recovery process by helping in the restoration of cartilages and functional bones. The working principle is simple; the pen makes use of cell material which is covered by a biopolymer, alginate, and then further engulfed by a gel. This cell material covered by two coatings comes out of the pen’s tip and allows the surgeon to literally draw in and fill the damaged area of the bone.

here is more from the experts themselves….

Doctors may soon be able to ‘draw’ new bone, skin and muscle on to patients, after scientists created a pen-like device that can apply human cells directly on to seriously injured people.

The device contains stem cells and growth factors and will give surgeons greater control over where the materials are deposited.

It will also reduce the time the patient is in surgery by delivering live cells and growth factors directly to the site of injury, accelerating the regeneration of functional bone and cartilage, scientists said.

The device developed at the University of Wollongong (UOW) will eliminate the need to harvest cartilage and grow it for weeks in a lab.

The BioPen works similar to 3D printing methods by delivering cell material inside a bio-polymer such as alginate, a seaweed extract, protected by a second, outer layer of gel material.

bio pen

The two layers of gel are combined in the pen head as it is extruded onto the bone surface and the surgeon ‘draws’ with the ink to fill in the damaged bone section.

A low powered ultra-violet light source is fixed to the device that solidifies the inks during dispensing, providing protection for the embedded cells while they are built up layer-by-layer to construct a 3D scaffold in the wound site.

Once the cells are ‘drawn’ onto the surgery site they will multiply, become differentiated into nerve cells, muscle cells or bone cells and will eventually turn from individual cells into a thriving community of cells in the form of a functioning a tissue, such as nerves, or a muscle.

The device can also be seeded with growth factors or other drugs to assist regrowth and recovery, while the hand-held design allows for precision in theatre and ease of transportation.

The BioPen prototype was designed and built using the 3D printing equipment in the labs at Wollongong and was handed over to clinical partners at St Vincent’s Hospital Melbourne, led by Professor Peter Choong, who will work on optimising the cell material for use in clinical trials.

“This type of treatment may be suitable for repairing acutely damaged bone and cartilage, for example from sporting or motor vehicle injuries,” Choong, Director of Orthopaedics at St Vincent’s Hospital Melbourne said.

Credit :NDTV

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